Rapid-Start Pilot PrEP Program Reduces HIV Incidence

Same-day PrEP initiation program for persons at elevated risk for HIV in rural Uganda and Kenya lowered HIV incidence by 74%.

Pre-exposure prophylaxis (PrEP) lowers risk for HIV infection, but uptake has been generally disappointing. In a study of population-level HIV testing of persons aged >15 in rural Uganda and Kenya, access to PrEP with enhanced counseling was provided for persons at elevated HIV risk (determined by partner serodifference, risk scores, or self-identified risk). Those at excess risk could initiate same-day PrEP with flexible delivery. Rapid antiretroviral treatment (ART) and laboratory assessments were provided for participants receiving PrEP who developed incident HIV infections. HIV incidence was compared with that among matched controls (persons in neighboring communities participating in the HIV testing project).

Of 74,451 persons negative …

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Rapid-Start Pilot PrEP Program Reduces HIV Incidence

Topics

Reviewing Author