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Rising antimicrobial resistance has spawned U.S. hospital stewardship programs aimed at guiding prescription practices supported by disease-state treatment standards plus documentation of clinical and microbiological evidence of infection. Researchers analyzed prevalence surveys of antimicrobial use in a cross-sectional sample encompassing 1566 patients at 192 hospitals in 10 states. Cases encompassed community-acquired pneumonia (CAP), urinary tract infection (UTI), fluoroquinolone treatment (FQ), or intravenous vancomycin treatment (VAN). Patients were evaluated for supported or unsupported antimicrobial use based on medical record data (signs and symptoms of infection, microbiology test results, antimicrobial treatment duration, deviatio…