Refining Estimated Risks for Hemorrhagic and Ischemic Stroke

In patients taking anticoagulants after a stroke or transient ischemic attack, a novel score including presence of cerebral microbleeds on MRI might aid in estimating recurrence risk.

Several trials and cohort studies have provided estimated risks for recurrent ischemic events after an ischemic stroke (IS) or transient ischemic attack. Whether the presence of cerebral microbleeds on imaging is useful to include in this prediction is uncertain. These authors evaluated more than 15,000 patients from 38 prospective studies. They developed a score to predict risk for intracerebral hemorrhage (ICH) or IS based on clinical variables (e.g., age, prior IS) and presence of cerebral microbleeds on MRI. Two separate scores (MICON-ICH and MICON-IS) were developed to predict risks for ICH and IS, respectively.

Among all the patients (mean age, 71 years; 42% women), 71% had hypertension and 44% had atrial fibrillation; 74% of patients …

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Refining Estimated Risks for Hemorrhagic and Ischemic Stroke

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Reviewing Author