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Recent observational studies suggest that exposure to modern intravenous radiocontrast dye (i.e., nonionic, iso- or low-osmolality agents) is not associated with adverse kidney outcomes. This evidence is compelling enough that a recent consensus statement from radiology and nephrology organizations deemed risk for contrast-associated kidney injury to be “overstated” (NEJM JW Gen Med Mar 15 2020 and Radiology 2020; 294:660).
In this latest study, researchers assessed kidney function in 156,000 adult emergency department patients (mean age, 53; mean estimated glomerular filtration rate [eGFR], 86 mL/minute/1.73 m2) who received D-dimer tests for suspected pulmonary embolism between 2013 and 2018 in Alberta, Canada, and did or did not undergo c…