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Whether and when to perform coronary angiography in patients successfully resuscitated from out-of-hospital cardiac arrest remain controversial. The randomized COACT trial examined the difference between immediate and delayed coronary angiography (with percutaneous coronary intervention as needed) in Dutch patients with out-of-hospital cardiac arrest but no ST-segment elevation myocardial infarction (non-STEMI) and found no significant difference in survival at 90 days (NEJM JW Cardiol May 2019 and N Engl J Med 2019; 380:1397; NTR4973). To determine whether immediate angiography would have later benefits, the COACT investigators analyzed outcomes at 1 year in 522 patients (95% of 552 enrolled participants).
Coronary angiography was performed…