Acute Stroke Treatment Outcomes in Patients with Cancer

Outcomes at 24 hours were similar in patients with and without active cancer, but those with active cancer had higher 6-month mortality.

Patients with active cancer have an increased rate of thrombotic events, including stroke. Whether to offer aggressive treatments such as endovascular thrombectomy (EVT) to patients with active cancer is a challenging decision, since intermediate and long-term survival may be poor. These authors conducted a multicenter study of patients with and without cancer who received either intravenous thrombolysis (IVT), EVT, or both. The primary outcomes of interest were 24-hour neurologic status, 3-month functional outcome, and 6-month survival. Active cancer was defined as a diagnosis within the past 6 months, current treatment with chemotherapy, or presence of metastatic disease.

Among 1338 patients (mean age, 68 years; 59% male), 4.6% had active …

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Acute Stroke Treatment Outcomes in Patients with Cancer

Topics

Reviewing Author