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The USPSTF last published colorectal cancer (CRC) screening guidelines for average-risk patients in 2016 (NEJM JW Gen Med Aug 1 2016 and JAMA 2016; 315:2564). They have now updated those recommendations and added a new recommendation for younger people (age range, 45–49). These guidelines apply to adults (age, ≥45) at average risk for colorectal cancer (i.e., no prior CRC, adenomatous polyps, or inflammatory bowel disease; no prior diagnosis or family history of genetic predisposition to CRC, such as Lynch syndrome).
The Task Force concludes with high certainty that CRC screening for middle-aged people (age range, 50–75) confers substantial bene…