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The nonpharmacologic interventions implemented to address the COVID-19 pandemic led to dramatic reductions in other viral respiratory tract infections (RTIs). As antibiotics are often inappropriately prescribed for viral RTIs, investigators sought to determine if the decline in RTIs was associated with a decrease in ambulatory antibiotic use. They compared respiratory virus detections and antibiotic prescriptions per 1000 patient encounters for both RTIs and non-RTIs at a single, large Midwestern academic health system before and during the COVID-19 pandemic.
Compared with pre-pandemic levels, detections of winter seasonal respiratory viruses (influenza, respiratory syncytial virus, and seasonal coronavirus) fell by >99% and detections of ot…