Living Longer with HIV Brings Consequences

HIV was associated with excess risk for frailty (although social, behavioral, and comorbidity-related factors accounted for much of this finding).

As persons living with HIV (PLWH) survive longer, their risk rises for age-related conditions such as frailty and the attendant falls and higher mortality. In this French observational study, 200 PLWH (age range, 55–70; viral load <50 copies/ml for the prior 24 months, CD4 count >200 cells/mm³ for the prior 12 months) were matched for age, sex, and education level with 1000 HIV-uninfected persons. Participants were assessed for frailty and prefrailty using criteria including body-mass index <21 kg/m², low physical activity, and weakness. Multivariate logistic regression was performed to measure the association between HIV and frailty or prefrailty adjusted for demographic, social, behavioral, and comorbidity confounders.

Data were available …

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Living Longer with HIV Brings Consequences

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Reviewing Author