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While most children who test positive for SARS-CoV-2 have brief illnesses, it's unclear how many have prolonged symptoms, and for what duration. In this prospective U.K. cohort study of COVID-19–positive school-aged children (range, 5–17 years), parents used a smartphone-based app to provide longitudinal data on symptom burden and illness duration. A total of 19 symptoms were measured. Results were grouped by children's age (5–11 years [younger] vs. 12–17 years [older]) and compared with a matched cohort of children who were negative for SARS-CoV-2 but symptomatic with other viral illnesses. Of 75,529 children with valid COVID-19 test results, 1734 who tested positive were included.
Overall, the most common symptoms were headache (62%) and f…