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In the past decade, several cities have offered acute stroke treatment with mobile stroke units (MSUs), in which an ambulance is equipped with a computed tomography (CT) scanning machine for rapid brain imaging and typically has a nurse onboard and remote physician supervision. The MSU model provides an opportunity for early stroke treatment, but limited data are available thus far on whether MSUs improve patient outcomes. In this randomized study, patients were treated with either an MSU or conventional emergency medical system (EMS) transport to the hospital on alternate weeks. Patients were provided tissue plasminogen activator (TPA) if they met standard clinical criteria and could be treated within 4.5 hours of stroke onset. The primary…