Do New Permanent Pacemakers Affect Outcomes After TAVR?

A nationwide Swedish study found no effect of pacemaker implantation on long-term survival.

New permanent pacemaker implantation (PPI) is required in up to 20% of patients after transcatheter aortic valve replacement (TAVR), but studies of outcomes in these patients show conflicting results. In this nationwide, population-based cohort study, researchers evaluated the effect of PPI on survival among all patients undergoing transfemoral TAVR in Sweden between 2008 and 2018 who survived at least 30 days postprocedure.

Among 3420 patients (mean age, 81 years; 50% women), 481 (14%) underwent PPI within 30 days after TAVR. Patients with previously implanted pacemakers were excluded from this study. Median follow-up was 2.7 years, and follow-up was complete. Multivariable analyses showed no differences in survival at 1, 5, and 10 years be…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)