Does Aspirin Use Before Stroke Improve Functional Outcome?

An observational study suggests that the answer is yes.

Despite changing recommendations, aspirin is widely used for both primary and secondary prevention of vascular events such as myocardial infarction and stroke. Previous studies (e.g., N Engl J Med 2020; 383:207) showed that 15% to 40% of patients with ischemic stroke are already taking aspirin at the time of stroke. These authors investigated functional outcome, thrombus burden, early neurologic deterioration (END), and hemorrhagic transformation in aspirin users versus nonusers. Thrombus burden was determined by the susceptibility vessel sign (SVS), and functional outcome was assessed at 3 months. Patients who received thrombolysis or thrombectomy were excluded.

Overall, 5700 patients (mean age, 67 years; 41% women) were included in the mul…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Does Aspirin Use Before Stroke Improve Functional Outcome?

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Reviewing Author