Time to Treatment and Outcomes in Basilar Artery Occlusion

In an observational study, onset-to-puncture time less than 4 hours was associated with better functional outcome than later treatment, but overall mortality was high.

Basilar artery occlusion (BAO) has long been recognized as an acute stroke syndrome with poor prognosis. Endovascular thrombectomy (EVT) has been established as effective treatment for select patients with large-vessel occlusion in the anterior circulation, but the role of EVT is not established for BAO. Now, researchers have evaluated the observational BASILAR clinical trial, conducted at multiple centers in China over a 5-year period. This analysis focused on neurologic outcomes according to time from symptom onset to start of treatment (groin puncture) in four categories: <4 hours, 4 to 8 hours, 8 to 12 hours, and >12 hours. The primary outcome was favorable functional outcome, defined as a modified Rankin scale score of 0 to 3 at 90 day…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Time to Treatment and Outcomes in Basilar Artery Occlusion

Topics

Reviewing Author