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In our annual review of important clinical research from the past year, we try to balance relevance to general medical practice and recognition of landmark studies and key guidelines. By any measure, the introduction of COVID-19 vaccination — and the ongoing pandemic despite the vaccine's effectiveness — was the top medical story of 2021. But this narrative is well known to virtually all readers now, and it is not easily compressed into a few hundred words. For this reason, we decided to omit COVID-19 vaccination from our 2021 Year in Review lineup.
The order of presentation of these summaries is not intended to reflect their relative importance.
Allan S. Brett, NEJM Journal Watch Editor-in-Chief