Post-Treatment HCV Reinfection in Those with HIV/HCV Coinfection

In a study across Europe, 7.3% of coinfected persons cured of their initial HCV infection were reinfected by 24 months.

Worrisome rates of HCV reinfection have been reported internationally among HIV/HCV coinfected patients after successful HCV treatment. Researchers for the EuroSIDA cohort study assessed 2-year prevalence of HCV reinfection in HIV/HCV coinfected persons who had received treatment with interferon (IFN)-based or IFN-free direct acting antivirals (DAA). Among 1022 patients (median age, 50; 78% male; 52% injection drug users), 62% had received IFN-free DAAs.

By 24 months, 7.3% of subjects had been reinfected, with rates of 16% for patients treated prior to 2014 versus 8.3% (IFN-based treatment) and 4.2% (IFN-free treatment) for those treated during or after 2014. After adjustment, patients treated after 2014 had significantly lower reinfection r…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Post-Treatment HCV Reinfection in Those with HIV/HCV Coinfection

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Reviewing Author