In a meta-analysis, outcomes were favorable overall.
Many studies have documented that the COVID-19 mRNA vaccines, while lifesaving, can also rarely cause myopericarditis, particularly in adolescents and young adults. Now, investigators have produced a systematic review and meta-analysis of those studies, focusing on people aged 12-20 years old.
The 23 observational studies included 854 people with myopericarditis after COVID-19 vaccination. Their mean age was 16 years, and 90% were males. Only 4% had a prior SARS-CoV-2 infection. None of the patients had prior cardiovascular disease.
Clinical characteristics and outcomes included the following:
Reviewing Author
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association