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NEJM Journal Watch General Medicine recently published a review of the 2022 American College of Gastroenterology (ACG) gastroesophageal reflux guideline. In a new conversation, Dr. Allan Brett (a general internist and Editor-in-Chief of NEJM Journal Watch General Medicine) and Dr. David Bjorkman (a gastroenterologist and former Editor-in-Chief of NEJM Journal Watch Gastroenterology) discuss some of the recommendations that are particularly relevant to practicing primary care clinicians. Click for NEJM Journal Watch's coverage of the guideline, and Dr. Brett's discussion with Dr. Bjorkman.