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Guidelines for treating patients with chronic, nonspecific low back pain (LBP) recommend both exercise and psychosocial therapies, but the comparative effectiveness of psychological interventions for LBP is unknown. Researchers conducted a network meta-analysis of 97 randomized, controlled trials in which different psychological interventions (alone or in combination with other treatments) were compared with nonpsychological interventions (e.g., physical therapy [PT], generalist care, no treatment) in >13,000 adults with chronic, nonspecific LBP.
Compared with PT alone, cognitive-behavioral therapy (CBT) plus PT was most effective for improving physical function (mean difference, 20 points on a standardized 100-point scale) within 2 months a…