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In watching network television just a few hours weekly, I've been struck by the sheer volume of direct-to-consumer (DTC) drug advertising. A recent advertising blitz for Tepezza (teprotumumab) — a medication for thyroid eye disease, or Graves orbitopathy — is particularly striking. The manufacturer obviously wouldn't spend money on these ads if they weren't influencing drug sales, but still I wondered about their impact. Researchers addressed this issue indirectly using Google Trends, a tool that tracks Google searches over time.
Findings were as follows:
Between 2004 and early 2019, a steady, but low-level, volume of searches was performed for “thyroid eye disease.”
In late 2019 (before Tepezza's U.S. FDA approval in January 2020), the compan…