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In large cohort studies, moderate coffee consumption has been associated with lower mortality (NEJM JW Gen Med Aug 15 2017 and Ann Intern Med 2017; 167:236, 228). Whether such an association holds true for sweetened coffee is unknown. U.K. investigators assessed outcomes in a prospective cohort of >170,000 people (mean age, 56) who were free from heart disease and cancer and who reported drinking unsweetened, sugar-sweetened, or artificially sweetened coffee — or no coffee. Analyses were adjusted for sociodemographic, lifestyle, and clinical variables.
Compared with nonconsumers, consumers of either unsweetened or sweetened coffee had significantly lower mortality after a median 7 years; the association was strongest for 2 to 4 cups daily (h…