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Because more than half of U.S. adults use at least one multivitamin, mineral, or other nutrient supplement, the USPSTF updated its 2014 recommendation regarding vitamin and mineral supplementation, based on a review of more than 50 studies that have been published since 2014 (NEJM JW Gen Med Jun 1 2014 and Ann Intern Med 2014; 160:558). The recommendations apply to community-dwelling, nonpregnant adults and do not apply to children, pregnant women, or people who are chronically ill or have known nutritional deficiencies.
The Task Force found no benefit and likely harm from use of β-carotene and lack of either benefit or harm from use of vitamin E, l…