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The association of COVID-19 with thrombotic events was initially inferred from case series. Now, investigators have analyzed U.S. claims and medical records data to evaluate incidence of inpatient arterial and venous thrombotic events among adults hospitalized with COVID-19 between April 1, 2020, and May 31, 2021 (41,443 before vaccine availability and 44,194 after). Controls comprised 8269 adults hospitalized with influenza during the 2018–2019 season.
The adjusted 90-day risk for developing arterial thrombosis was no different between patients with COVID-19 or influenza, both before and after COVID-19 vaccine availability (hazard ratio [HR], 1.04–1.07). In patients who experienced an arterial thrombotic event, subsequent 30-day mortality r…