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Ultraviolet-C (UV-C) disinfection of patients' rooms has a variable effect on incidence of hospital-onset Clostridioides difficile and vancomycin-resistant enterococcal infections (NEJM JW Infect Dis Dec 2021 and Clin Infect Dis 2021 Oct 12; [e-pub]), but the effect on hospital-onset gram-negative rod bloodstream infection (HO-GNR BSI) is unknown. Researchers evaluated the incidence of HO-GNR BSI at 120 Veterans Administration (VA) hospitals (40 with UV-C disinfection and 80 without) between 2010 and 2018.
Among 13,383 HO-GNR BSI episodes throughout the study period, incidence declined at a rate of −0.43% per month. Implementation of UV-C disinfection was associated with a significant decrease of 19% in HO-GNR BSI, but the effect varied by h…