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Ischemic stroke incidence has long been known to vary among ethnic groups. But whether there are ethnic disparities in the patterns of recovery following ischemic stroke is less well understood. To address this issue, investigators conducted a population-based, longitudinal study that compared outcomes after a first ischemic stroke between 807 Mexican American (MA) patients and 525 non-Hispanic white (NHW) patients in a biethnic community in southern Texas. The study assessed outcomes at 3, 6, and 12 months in several domains, including functional outcome, quality of life, neurologic status (measured by the NIH Stroke Scale), and cognitive outcomes (using a modified Mini-Mental Status Examination).
MA patients were younger than NHW patients (median 65 vs. 70 years), were less likely to have attained a high school or higher level of education (58% vs. 92%), and were more likely to be uninsured (17% vs. 9%). There was no difference in the comorbidity index and no statistical difference in alteplase use for the index stroke. In both ethnic groups, outcomes improved between 3 and 6 months. However, MA patients had worse outcomes compared with NHW patients at all time points, with the exception of outcomes measured by the NIH Stroke Scale.
Lisabeth LD et al. Outcomes in the year after first-ever ischemic stroke in a bi-ethnic population. Ann Neurol 2022 Sep 22; [e-pub]. (https://doi.org/10.1002/ana.26513)
Comment
This study indicated that MA patients had mildly worse outcomes after stroke compared with NHW patients. Further efforts are needed to address factors that could improve early outcomes in MA persons, such as greater intensity of therapy. Whether medication adherence varies between the two groups also deserves further study.