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Although exercise has been a longstanding guideline-recommended therapy for patients with osteoarthritis (OA), whether higher “dosing” of therapy (by duration and intensity) can yield incremental improvements in symptoms, function, or quality of life (QOL) is unknown. Scandinavian researchers randomized 189 patients (average age, 62) with symptomatic knee OA to receive either high-dose (11 exercises over 70–90 minutes) or low-dose (5 exercises over 20–30 minutes) exercise therapy thrice weekly for 12 weeks; all sessions were supervised by physiotherapists.
At the end of the 3-month intervention and after 6 and 12 additional months of follow-up, both groups achieved similar improvements in knee-pain scores and activities of daily living. Pati…