Low Serum Creatinine: Marker for Adverse Perioperative Outcomes?

Preoperative serum creatinine levels lower than 0.65 — and especially lower than 0.45 mg/dL — were associated with excess postoperative complications and death.

Low serum creatinine levels are associated with sarcopenia and frailty, which in turn predict adverse perioperative outcomes. In this study, researchers examined whether low preoperative serum creatinine correlated with mortality and complications after nonemergent inpatient surgery. The source of data was the U.S. National Surgical Quality Improvement Program; patients with conditions known to raise or lower serum creatinine acutely or subacutely were excluded.

In analyses adjusted for numerous demographic characteristics and comorbidities, the following 30-day postoperative outcomes were noted among 1.8 million adults:

Compared with patients whose preoperative serum creatinine was between 0.65 and 1.04 mg/dL, those with serum creatinine low…

Reviewing Author

Allan S. Brett, MD

Disclosures

Nothing to disclose

Allan S. Brett, MD

Disclosures

Nothing to disclose

Low Serum Creatinine: Marker for Adverse Perioperative Outcomes?

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Reviewing Author