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Low-grade asymptomatic microscopic hematuria often is overlooked in primary care practice. To examine how often microscopic hematuria predicts later development of chronic kidney disease (CKD), Korean researchers used data from a cohort study that involved 230,000 adults (mean age, 38) without CKD or urinary tract malignancy at baseline. All participants had “comprehensive health examinations” about 2 years apart that included urinalysis and measurement of renal function. Microscopic hematuria was defined as >5 red cells per high power field.
During median follow-up of 5 years, the incidence of CKD — defined as estimated glomerular filtration rate (GFR) <60 mL/minute/1.73 m2 or dipstick proteinuria of 1+ or higher (≥100 mg/dL) — was 1% in pe…