Tau Positron Emission Tomography: Another Clinically Useful Tool?

Tau positron emission tomography influenced clinical decision making in memory clinic patients.

Amyloid and tau pathology are seen in Alzheimer disease (AD). In this prospective cohort study, researchers investigated how tau positron emission tomography (PET) with [18F]RO948 influenced the diagnosis, treatment plans, and diagnostic certainty for 878 memory clinic patients with cognitive complaints. Patients underwent a clinical workup, including cognitive testing, cerebrospinal fluid (CSF) sampling, and structural MRI. Managing physicians completed a form before and after the PET scan to identify the clinical stage of patients (subjective cognitive decline, mild cognitive impairment [MCI] or dementia), the etiologic diagnosis (AD or non-AD), their diagnostic confidence, and their defined treatment plan with cognitive-enhancing medicat…

Reviewing Author

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Tau Positron Emission Tomography: Another Clinically Useful Tool?

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Reviewing Author