A meta-analysis of randomized trials suggests a benefit, but stronger data are still needed.
Post-thrombotic syndrome (PTS) — characterized by skin itchiness, leg swelling, discoloration and thickening, and, if advanced, ulcers — is a common chronic complication of deep venous thrombosis (DVT), occurring in 20% to 50% of patients after a DVT. To date, randomized trials of elastic compression wearables for prevention of PTS have shown inconsistent results, and practice guidelines recommend against their routine use in acute DVT (Chest 2021; 160:e545). However, additional small trials have emerged recently. Now, investigators report results of a systematic review and meta-analysis of randomized trials assessing the effect of wearing compression stockings on prevention of PTS, and the optimal duration of wear, after an acute DVT.
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Reviewing Author
DisclosuresGrant/Research SupportBrigham and Women’s Hospital; American Heart Association and VIVA Physicians
Editorial BoardsThrombosis Research; Thrombosis and Haemostasis; Journal of the American College of Cardiology
Leadership Positions in Professional SocietiesSociety for Vascular Medicine (Research, Quality, and Publications Committee member); International Society on Thrombosis and Haemostasis
DisclosuresGrant/Research SupportBrigham and Women’s Hospital; American Heart Association and VIVA Physicians
Editorial BoardsThrombosis Research; Thrombosis and Haemostasis; Journal of the American College of Cardiology
Leadership Positions in Professional SocietiesSociety for Vascular Medicine (Research, Quality, and Publications Committee member); International Society on Thrombosis and Haemostasis