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Many guidelines recommend ≥150 minutes of moderate-to-vigorous physical activity (MVPA) weekly to lower risk for heart disease, but do such benefits depend on how that exercise is distributed? Investigators used a U.K. data registry to explore benefits of “weekend warrior” exercise (i.e., half or more of 150 minutes of MVPA weekly occurring in 1–2 days) by identifying 90,000 people (mean age, 62) who had recorded, accelerometer-based physical activity. About 40% were classified as weekend warriors, 25% were regular exercisers (≥150 minutes of MVPA distributed throughout the week), and 35% were inactive (<150 minutes of MVPA weekly).
In analyses adjusted for potentially confounding factors, risks for several types of incident heart disease we…