Quantifying the region- and sex-specific consequences of these risk factors can help to shape policy efforts and patient care.
We know the traditionally identified modifiable cardiovascular risk factors: body-mass index, systolic blood pressure, non–high-density lipoprotein cholesterol level, tobacco smoking, and diabetes. But what are their quantifiable global consequences? Investigators pooled individual-level data from 112 cohort studies in 34 countries and 8 geographic regions to assess the regional and sex-specific prevalence of these risk factors and their worldwide impact (NCT05466825).
The combined studies involved more than 1.5 million participants (mean age, 54 years; 54% women). The incidence of age- and sex-standardized 10-year cardiovascular disease events varied by region (10% in North America, 8% in North Africa and the Middle East, 8% in Eastern Euro…
Reviewing Author
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association