Optical Coherence Tomography Guidance for Percutaneous Coronary Intervention

Despite an improvement in technical outcomes, optical coherence tomography guidance did not result in improved clinical outcomes for patients undergoing complex PCI.

Historically, percutaneous coronary intervention (PCI) has been guided by coronary angiography. In recent years, numerous clinical trials have demonstrated that intracoronary imaging using intravascular ultrasound (IVUS) can provide more accurate measurements of coronary artery dimensions and visualize structures that coronary angiography cannot — atherosclerotic plaque, stent underexpansion, and localized coronary dissections — leading to improved PCI outcomes. Optical coherence tomography (OCT) is another form of intravascular imaging that provides higher resolution and superior plaque imaging than IVUS, but its impact on PCI outcomes remains unknown.

In the industry-sponsored, multinational, single-blind ILUMIEN-4 trial (NCT03507777), inv…

Reviewing Author

David J. Cohen, MD, MSc

Disclosures

Consultant/Advisory BoardMedtronic; Edwards Lifesciences; Abbott Vascular; Boston Scientific; St. Francis Hospital

Speaker’s BureauBoston Scientific; ZOLL Medical

Grant/Research SupportEdwards Lifesciences; Abbott Vascular; Boston Scientific; Corvia Medical; National Heart, Lung, and Blood Institute; Phillips, Inc.; St. Paul’s Hospital; V-Wave, Inc; ZOLL Medical; CathWorks, ANCORA

Editorial BoardsJACC; American Heart Journal; EuroIntervention; JSCAI; Structural Heart Journal

Leadership Positions in Professional SocietiesSociety of Thoracic Surgeons/American College of Cardiology TVT Registry (Co-Chair, Risk Model Development Committee); Cardiovascular Research Foundation (Co-Director, TCT Annual Meeting; Co-Director, New York Valves Annual Meeting)