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At 1 year after acute COVID-19, survivors still had excess risk for persisting symptoms and development of new diseases. Have these risks persisted at the end of 2 years? Investigators from the U.S. Veterans Affairs health system compared risks in nearly 139,000 people surviving acute COVID-19 (hospitalized and nonhospitalized subgroups) and nearly 6 million people never diagnosed with COVID-19.
After 2 years, while the excess risks seen at 1 year had attenuated somewhat, many persisted. Compared with the no-COVID group, relative risks in the hospitalized and nonhospitalized subgroups were fatigue, 1.9/1.2; anosmia, 2.2/2.2; dyspnea, 2.0/1.2; impaired memory, 1.7/1.1; cognitive decline, 1.7/1.2; acute coronary disease, 1.3/1.0; pulmonary emb…