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Select patients with a large-vessel occlusion can benefit from endovascular thrombectomy (EVT) within 24 hours of stroke onset. After the procedure, the optimal blood pressure (BP) is uncertain. Theoretically, intensive BP lowering can reduce the risk of symptomatic intracerebral hemorrhage (sICH), but it could also result in brain hypoperfusion. Two recent studies have addressed this topic.
In a randomized trial from 19 centers in South Korea, Nam and colleagues randomized patients after EVT to either intensive BP lowering (aiming for <140 mm Hg systolic) or the conventional BP goal (140–180 mm Hg systolic). BP was intended to be within these parameters for the first 24 hours. The primary outcome was functional independence at 90 days, defi…