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Gastroparesis and functional dyspepsia are sensorimotor disorders with similar symptoms. Some authorities suggest that they are variations on the same disorder (NEJM JW Gen Med Jun 15 2021 and Gastroenterology 2021; 160:2006), whereas other experts believe that they are distinct entities with overlapping symptoms that require different treatments.
In this study, investigators reviewed data on 339 patients referred to a U.S. tertiary center for presumed gastroparesis. Gastroparesis was the final diagnosis in only 20% of these patients. Functional dyspepsia was diagnosed in 46%, and alternative diagnoses were made in the remaining patients. However, no differences were noted across these groups in presenting symptoms (i.e., nausea, abdominal p…