Management and Prevention of Syphilis: 2023 Update

New guidelines on syphilis management detail screening, treatment, and monitoring for serologic response.

Sponsoring Organization: Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV

Target Audience: Internal medicine physicians, obstetrician-gynecologists, midwives, infectious disease specialists, and providers in sexual health/STI clinics

Background

The incidence of syphilis in the U.S. (including syphilis in pregnancy and congenital syphilis) has continued to rise throughout the last 2 decades. These guidelines update the recommendations for management and prevention of syphilis in adults and adolescents with and without HIV.

Key Recommendations and Updates

The principles of diagnosis and management of syphilis are the same for people with and without HIV; however, neurosyphilis and …

Reviewing Author

Anna Wald, MD, MPH

Disclosures

Consultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)

RoyaltiesUpToDate

Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris

Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases

Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)