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Cardiopulmonary rehabilitation programs are a cornerstone of managing chronic obstructive pulmonary disease and cardiovascular disorders and improve patients' symptoms, exercise capacity, and quality of life (QoL). Among patients with acute pulmonary embolism (PE) who receive guideline-directed treatment, as many as 50% will develop long-term sequela of dyspnea and poor QoL, sometimes termed “post-PE syndrome,” a condition without any well-studied therapeutic interventions.
Researchers in Norway identified 211 patients who had persistent dyspnea at 6 to 72 months after acute PE but no evidence of chronic thromboembolic pulmonary hypertension or other cardiopulmonary comorbidities. Patients were randomized to twice-weekly sessions of physical…