No Sex-Based Differences in Outcomes of Pulsed Field Ablation for Atrial Fibrillation

Early studies evaluating differences between men and women undergoing atrial fibrillation (AF) ablation indicated that women might have worse outcomes, including a lower success rate and more complications. However, some later studies did not confirm that sex-based disparity. In a large, retrospective cohort study, investigators further examined this issue.

The analysis included 1568 patients (65% men) from a registry of patients who underwent first-time pulsed field ablation of AF in Europe and was funded by the manufacturer of the non–FDA-approved catheter used in the registry. Compared with men, women were older, had more paroxysmal AF, and had fewer comorbidities such as coronary heart disease, heart failure, and sleep apnea. Nearly 100%…