Among U.S. Transgender Persons, HIV Testing and PrEP Prescriptions Have Increased During the Past Decade

Transgender persons have increased risk for HIV infection, with estimated prevalence of 14.1% for transgender women (TGW) and 3.2% for transgender men (TGM), with higher rates among Black and Latino individuals. Medical appointments for gender-affirming hormone therapy represent opportunities for HIV testing and PrEP prescribing. Using a U.S. commercial insurance database, investigators identified adults with transgender-related diagnostic codes between 2014 and 2021.

Transgender-related diagnoses increased from 13.4 to 113.9 per 100,000 insured persons, primarily driven by those aged 18–34 years. Prescription of gender-affirming hormone therapy also increased (from 30.5% to 43.4% of transgender individuals). Approximately 2.4% of TGW and 0.…