Do Higher PrEP Costs Affect Risk for Subsequent HIV Infection?

Models based on insurance data indicate that increasing copays for PrEP raise risk for unfilled prescriptions and associated HIV infection.

Uptake of PrEP among U.S. persons at risk for HIV infection remains disappointingly low as out-of-pocket costs threaten access. To determine the impact of copays on initial PrEP fill rates among persons with insurance-approved PrEP, investigators queried a proprietary database containing claims for 80%–85% of all PrEP prescriptions in the U.S. from 2015 to 2019. Initial PrEP fill rates were determined across 6 out-of-pocket cost categories ranging from $0 to >$500, and a model was developed to simulate changes in such expenses and rates of subsequent diagnoses of HIV infection relative to those expenses. Data were analyzed from 58,529 persons with new insurance-approved PrEP and no documentation of an existing HIV diagnosis or reason to tak…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Do Higher PrEP Costs Affect Risk for Subsequent HIV Infection?

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Reviewing Author