Adverse Outcomes Following Curative Treatment for Prostate Cancer

Patients with clinically localized prostate cancer are typically offered an array of treatment options that may include active surveillance; radical prostatectomy; and radiotherapy, with or without androgen-deprivation therapy (ADT). No prospective data on disease outcomes provide support for either surgery or radiotherapy, therefore many patients make treatment decisions based on their understanding of the potential impact on urinary, sexual, or bowel function.

Investigators evaluated treatment-related functional outcomes in an observational study of 2445 patients treated for localized prostate cancer who were enrolled in the Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study. Patients were divided into two groups at…