Diagnosis and Management of Cryptococcosis — A Global Synthesis

Background

Cryptococcosis remains a global challenge, particularly in low- and middle-income countries with high incidence of HIV infection. Although other guidelines for cryptococcosis exist, these recommendations — integrated by an international group of cryptococcal experts — explore areas of uncertainty and articulate viewpoints from different geographic regions and settings.

Key Points and Recommendations

• The various phases and anatomical sites of cryptococcal infection affect antifungal therapy differently.

• Liposomal amphotericin B (3–4 mg…