Vibration-Controlled Transient Elastography in Patients with Steatotic Liver Disease

Previous studies have shown that noninvasive methods, such as vibration-controlled transient elastography (VCTE; FibroScan), can identify fibrosis with reasonable accuracy in patients with metabolic dysfunction–associated steatotic liver disease (MASLD; until recently, known as NAFLD). Now, in a large cohort study, researchers have examined the accuracy of VCTE — in combination with laboratory and clinical data — to predict important clinical outcomes.

The study involved nearly 17,000 patients (mostly from Korea, Hong Kong, and Italy) with steatosis on imaging or liver biopsy and no history of excessive alcohol use or liver diseases other than MASLD. All patients underwent VCTE and had calculation of Agile 3+ and Agile 4 scores, which incorp…