Loading...
Patients with obstructive sleep apnea (OSA) are at higher risk for major adverse cardiovascular events (MACE). While obesity is a strong risk factor for OSA, it is unknown whether intentional weight loss decreases the risk for MACE or death in these patients.
To examine this possibility, investigators retrospectively compared outcomes between nearly 1000 adults with moderate-to-severe OSA who underwent bariatric surgery for a body-mass index (BMI) of 35–70 kg/m2 and nearly 13,000 patients with OSA and obesity who did not undergo surgery. The primary endpoint was the first occurrence of MACE, which included coronary artery events, cerebrovascular events, heart failure, atrial fibrillation, and all-cause death.
At 10 years, mean weight loss was…