Do Hypertension and Antihypertensive Use Affect Dementia Risk?

Hypertension is a risk factor for all-cause dementia. Using individual patient data from an international cohort of 31,250 participants of studies from 14 European, African, Asian, North American, and South American countries and Australia (41% male; mean age, 72 years; mean baseline blood pressure 138/80 mm Hg), researchers in this study determined whether antihypertensive use was associated with incident dementia in three participant categories: a control group without a hypertension history or antihypertensive use at baseline, a treated hypertension group with a history of hypertension and antihypertensive use who were normotensive at baseline, and an untreated hypertension group with hypertension at baseline and no antihypertensive use.…