Time in Blood Pressure Target Range and Outcomes in Hypertension: Real-World Data

Observational data confirm an association between longer time in target range and reduced incidence of CVD and premature death.

In patients with hypertension, the proportion of time in which blood pressure (BP) is outside of the targeted range has been associated with adverse cardiovascular events and mortality in post hoc analyses of clinical trials. A recent prospective cohort study provides data from a real-world setting.

The cohort included 9552 participants in a workplace hypertension management program in Tangshan, China (mean age, 48 years; 96% men). The employees were receiving antihypertensive medication and underwent BP monitoring for at least 6 months. Target systolic BP was defined as 120–140 mm Hg, and time in target range was calculated using linear interpolation. Cardiovascular disease (CVD) was defined as fatal or nonfatal myocardial infarction (MI) o…

Reviewing Author

Karol E. Watson, MD, PhD, FACC

Disclosures

Consultant/Advisory BoardBoehringer Ingelheim; Amgen; Novartis; Lilly; Amarin

Speaker’s BureauBoehringer Ingelheim

Grant/Research SupportNIH

Editorial BoardsCirculation (Associate Editor)