Sex-Based Disparity in CABG Outcomes: Are We Moving Toward Parity?

Historically, women undergoing coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) have had worse outcomes than men undergoing these procedures. With the advent of new medical therapies and procedural techniques, this gap may be narrowing. To find out, researchers analyzed subgroup data from the global FAME 3 trial (NCT02100722), which randomized patients to fractional flow reserve (FFR)–guided PCI or CABG for multivessel coronary artery disease.

Among 1500 patients (82% men; mean age, 65 years; 93% white), women were older than men and had more comorbidities and less-complex coronary artery disease. At 3 years, the incidence of death, myocardial infarction (MI), stroke, or repeat revascularization (the primar…