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Target Audience: Pulmonary and critical care providers
An expert panel identified the two most relevant new fungal topics since the prior guidelines were published in 2011. The panel applied literature review with data evaluation and the GRADE (grading of recommendations, assessment, development, and evaluation) approach.
1: Should combination therapy with a mold-active triazole plus an echinocandin be preferred over triazole monotherapy for invasive pulmonary aspergillosis (IPA)?
IPA is most likely to occur in those with prolonged neutropenia, particularly after hematopoietic stem cell transplantation. It may also be seen in those receiving high-dose cortic…