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Some patients with migraine experience transient focal neurologic symptoms (the “aura”) just before or accompanying the onset of headache. However, primary care clinicians might not be familiar with a non-aura “prodrome” that is sometimes the earliest phase of a migraine. In this report, researchers describe prodromal symptoms in ≈900 patients with frequent migraine who were aware of prodromes that usually preceded (by 1–6 hours) a migraine headache. Participants kept symptom diaries for 60 days as part of a previously published, industry-sponsored trial in which the CGRP antagonist ubrogepant (Ubrelvy) — administered at onset of the prodrome — improved migraine outcomes compared with placebo (NEJM JW Neurol Dec 15 2023 and Lancet 2023; 402…